Research Interest::

- Lab-on-a-Chip (uTAS), BioMEMS
- Micro-Bio-Nanotechnology for Medical/Bio Applications
- Micro and Nano Fluidic Systems
- Bio-Nano Interfacing and Packaging

Research activities in the NanoBio Systems Lab. include the development of miniaturized systems for cellular and molecular analysis using micro and nano fabrication technologies. Micro and nanofluidic based systems with integrated analysis techniques enable fast and accurate analysis at low cost and portable setting. Micro and nanofabrication of silicon, glass, and polymer are being used in my lab to realize such system. I have interest in developing systems that can analyze and control various physiological properties of individual cells in an array format. Cancer cells and neuronal cells are of particular interest. I also have interest in utilizing the unique properties of micro and nano scale fluidic phenomena to develop novel systems and interface those systems with biological systems.


Lab. News ::

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NEW. November 13, 2009
Jaewon Park's journal paper titled "Microfluidic Compartmentalized Co-culture Platform for CNS Axon Myelination Research" has been published in Biomedical Microdevices (J. Park, H. Koito, J. Li, and A. Han, “Microfluidic Compartmentalized Co-culture Platform for CNS Axon Myelination Research,” Biomedical Microdevices, Vol. 11, pp. 1145-1153, 2009). Congratulations!!!

 

NEW. November 3, 2009
Jaewon Park presented two posters titled "Multi-Compartment CNS Neuron-Glia Co-culture Platform" and "Precision Patterning of Poly(dimethyl siloxane) as an Electrical Insulating Layer using Photoresist Lift-off Process" at the 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2009) held in Jeju, Korea.

NEW. October 22, 2009
Huijie Hou's journal paper titled "A thermoresponsive hydrogel poly(N-isopropylacrylamide) micropatterning method using microfluidic techniques" was published in the Journal of Micromechanics and Microengineering (H. Hou, W. Kim, M. Grunlan, and A. Han, "A Thermoresponsive Hydrogel Poly(N-isopropylacrylamide) Micropatterning Method using Microfluidic Techniques, Journal of Micromechanics and Microengineering, Vol. 19, pp. 127001, 2009.). Woosik Kim is the second author on this paper. Congraulations!!!

 

September 11, 2009
The First Texas A&M University Nano/Micro Poser Symposium wasa great success with more than 65 posters and 150 participants throughout the campus. As part of the opening talk as well as the inaugural talk for the newly launched monthly Texas A&M Nano/Micro Semianr Series, Prof. Mauro Ferrari, a world-renowened expert in nanomedicine gave talk titled "Three DImensions of Individualized Nanomedicine". Thank for you all the group members who helped this event. Click here for full story in the Texas A&M Engineering News.

August 22, 2009
Two new members joined the group. Jianzhang Wu is joining as a Ph.D. student and Han Wang is joining as a M.S. student. Welcome to the group.

 

August 14, 2009
The new NSF grant for developing microbial fuel cell array and the related recent paper in PLoS One featured in Texas A&M Engineering News. Click here for full story.

August 10, 2009
Younghak Cho, a former member and currently an Assistant Professor at Seoul National University of Technology in Korea, publishes his paper titled "Whole-Cell Impedance Analysis for Highly and Poorly Metastatic Cancer Cells" in the Journal of Microelectromechanical Systems (Y. Cho, H. S. Kim, A. B. Frazier, Z. G. Chen, D. M. Shin, and A. Han, J. Microelectromechanical Systems, Vol. 18 (4), pp. 808-817, 2009). Hyunsoo Kim, Ph.D. student, is the second author of this paper. Congratulations!!!

 

August 10, 2009
Huijie Hou's paper titled "Microfabricated Microbial Fuel Cell Arrays Reveal Electrochemically Active Microbes" published in the journal PLoS ONE (H. Hou, L. Li, Y. Cho, P. de Figueiredo, and A. Han, PLoS ONE, Vol. 4 (8), pp. e6570, 2009). Former member Dr. Younghak Cho is also a co-author in this paper. Congratulations!!!

 

August 5, 2009
Prof. Arum Han gave a talk titled "Microsystems for Biology" at the Institute of Industrial Science, University of Tokyo, Japan.

 

June 6, 2009
Prof. Arum Han gave a talk titled "Microsystem Platform for Cell Culture and Cell Analysis" at Inje University, Korea.

 

May 20, 2009
Jaewon Park and Hyunsoo Kim's journal paper titled "Micropatterning of Poly(dimethylsiloxane) using a Photoresist Lift-off Technique for Selective Electrical Insulation of Microelectrode Arrays" published in the Journal of Micromechanics and Microengineering (J. Park, H. S. Kim, and A. Han, J. Micromech. Microeng. Vol. 19, pp. 065016, 2009). Congratulations!!!

 

March 19, 2009
Prof. Arum Han and four of his students, Jaewon Park, Hyunsoo Kim, Huijie Hou, and Woosik Kim, gave four oral presentations and one poster presentation at the 26th Annual Houston Conference on Biomedical Engineering Research (HSEMB), Houston, TX. The presented papers are as following.

Huijie Hou, Ph.D. student, gave an oral presentation titled "Thermosensitivity and Surface Properties of Microstructured Poly (N-Isopropylacrylamide) for Regulated Cell Release."

Hyunsoo Kim, M.S. student, gave an oral presentation titled "Whole Cell Impedance Spectroscopy Microsystem for Highly-Metastatic and Poorly-Metastatic Cancer Cell Analysis."

Jaewon Park, Ph.D. student, gave an oral presentation titled "Microfluidic Co-Culture Platform for CNS Axon-glia Interaction."

Woosik Kim, M.S. student, presented his poster titled "A Method for Poly(N-Isopropylamide) Micropatterning Controlled by Microfluidics."

Prof. Arum Han gave an oral presentation titled "Nanochannel Fabrication for Single DNA Analysis."

 

February 28, 2009
Dr. Younghak Cho who worked as a postdoctoral researcher for the past year and half in our lab is joining the Mechanical Engineering Department at the Seoul National University of Technology as an Assistant Professor as of March 31, 2009. Congratulations !!!

 

February 27, 2009
Prof. Han's recent grant award from the National Institutes of Health / National Institute for Biomedical Imaging and Bioengineering (NIH/NIBIB) to develop and apply microsystems for neuroscience research in collaboration with Prof. Jianrong Li in the Veterinary Integrative Biosciences was featured in the Texas A&M Engineering news (click here for full news).

January 28, 2009
Hyunsoo Kim , M.S. student, presented his poster titled " Whole Cell Impedance Analysis of Metastatic and Non-metastatic Head-and-Neck Cancer Cells," at the 22nd IEEE International Conferece on Micro Electro Mechanical Systems, Sorrento, Italy.