Welcome to the NanoBio Systems Lab


 

Research Interest::

The NanoBio Systems Laboratory is interested in solving grand challenge problems in the broad area of health and energy through the use of micro/nano systems technology. Our effort is multidisciplinary, encompassing expertise from engineering (electrical, biomedical, mechanical, chemical, computer), physical science (chemistry), and life sciences (neuroscience, microbiology, cancer biology, biochemistry, plant pathobiology, veterinary medicine, agriculture).

Our current research themes are microphysiological systems (organ-on-a-chip), metastatic cancer analysis, microbes as biorefinery, and microbial physiology and functions in infectious disease.

 

Research Funding:

Research in the NanoBio Systems Laboratory is supported by the Bill and Melinda Gates Foundation, National Institutes of Health (NIH, National Institute of Mental Health (NIMH) and National Institute of Biomedical Imaging and Bioengineering (NIBIB)), National Science Foudnation (NSF) (Emerging Frontiers in Research and Innovation (EFRI), CBET, ECCS), Defense Threat Reduction Agency (DTRA), United States Department of Agriculture (USDA), U.S. Army Corp of Engineer, Korean Ministry of Knowledge Economy, Qatar National Research Foundation (QNRF), and Samsung Electronics, Inc.

 

Lab. News ::


Click here for archive

Oct. 1, 2017
Our work on microfludic systems for algal biofuel featured on Boyce Thompson Institute (BTI) news story. Click here for more details.

Cornell Chronicle also published a story on this work. Click here for more details.

 

Sep. 28, 2017
Hyunsoo, Song-I, and Adrian's paper publishsed in the journal Plant Direct (High-throughout Droplet Microfluidics Screening Platform for Selecting Fast-growing and High Lipid-Producing Microalgae from a Mutant Library). Congratulations Hyunsoo and All!

 

Sep. 15, 2017
Kevin Cushing joined our lab as a postdoctoral researcher. Lanchun He joined our group as a PhD student. Welcome to the group~

 

August 10, 2017
Jose Wippold, PhD student in our lab, received the 2017 Science, Mathematics & Research for Transformation (SMART) fellowship from the Department of Defense (DoD). Click here for Engineering News. Congratulations Jose!!

 

June 6, 2017
Song-I Han's paper publishsed in the journal Biosensors and Bioelectronics (In-Droplet Cell Concentration using Dielectrophoresis). Congratulations Song-I!

 

May 4, 2017
We successfully organized the 4th Annual Texas A&M ENG-LIFE workshop focusing on multidisciplinary research. Thank you for all the help. Click here to see the Engineering News.

Apr. 18, 2017
Stephanie Wilcox places was awarded first place in the technology and engineering poster presentation category at the Emerging Researchers National (ERN) Conference in Science, Technology, Engineering and Mathematics (STEM), held in Washington, D.C. Congratulations Stephanie. Congratulations Stephanie!!
Click here to see the Engineering News.

Also see another Engineering News article "Rising seniors at a glance: Stephanie Wilcox"

Mar. 8, 2017
Prof. Han among inaugural class of Texas A&M's Presidential Impact Fellow. The program was established to recognize rising stars in their respective fields, and those who embody the university’s commitment to advancing knowledge through transformational learning, discovery, innovation and impact for Texas and the world.
Click here to see the Engineering News.
Click here to see the news published at The Eagle.

 

Mar. 6, 2017
Hyunsoo's paper published in the journal Analyst (Raman spectroscopy compatible PDMS droplet microfluidic culture and analysis platform towards on-chip lipidomics). Congratulations Hyunsoo!

 

Feb. 24, 2017
Nebras' paper published in the journal Lab on a Chip (Impedance spectroscopy-based cell/particle position detection in microfluidic systems). Congratulations Nebras!!

 

Dec. 7, 2016
We are part of a new $4.2 million NIH Tissue Chip Testing Center (TCTC).
Click here for Engineering News.
Also see announcement from NIH/NCATS here.

For the KBTX article and video, click here.

 

Dec. 1, 2016
Former PhD student and postdoctoral researcher Dr. Han Wang joined the prestigious Tsinghua University Medical Systems Biology Research Center, Department of Biomedical Engineering, School of Medicine, Tsinghua University, as a Research Assistant Professor. Many Congratulations Han!!

 

Sep. 1, 2016
We are welcoming four new members this Fall. Can Huang, Amirali Selahi, and Reihaneh Toutouni are starting their PhD program. Karthik Shankar is starting his MS program. Welcome to the group.

 

August 31, 2016
Celal Erbay received the best PhD student award from the Department of Electrical and Computer Engineering. Many congratulations! Click here for more information.

 

June 28, 2016
Hyunsoo's paper published as front cover in the journal Biotechnology and Bioengineering (H. S. Kim, A. R. Guzman, H. R. Thapa, T. P. Devarenne, and A. Han, "A Droplet Microfluidics Platform for Rapid Microalgal Growth and Oil Production Analysis," 2016). Congratulations Hyunsoo! Click here to see the TAMU Engineering News Article.

May 11, 2016
Prof. Han receives the 2016 Dean of Engineering Excellence Award. See announcement here.

 

Apr. 29, 2016
The 2016 ENG-LIFE Workshop we organized another big success. See TEES news here.

Apr. 28, 2016
Celal successfully defenced his PhD dissertation defense. Congratulations Dr. Erbay!

 

Mar. 2, 2016
Celal's joint firth author paper has been published in the journal Nano Energy (G. Yang, C. Erbay, S. Yi, P. de Figueiredo, R. Sadr, *A. Han, and *C. Yu (*co-corresponding authors), "Biofunctional Nano-Sponges Serving as Non-Precious Metal Catalysts and Self-Standing Cathdoes for High Performance Fuel Cell Applications," Nano Energy, Vol. 22, pp. 607-614 (2016)). Congratulations Celal!

 

Feb. 11, 2016
Jing Dai's paper has been published in teh journal RSC Advances (J. Dai, H. S. Kim, A. R. Guzman, W. -B. Shim, and A. Han, "A Large-scale On-Chip Droplet Incubation Chamber Enables Equal Microbial Culture Time," RSC Advances, Vol. 6, pp. 20516-20519 (2016). Congratulations Jing!

 

Jan. 27, 2016
Han Wang's paper has been published in the Journal of the Acoustic Society of America (Z. Liu, Y. -J. Kim, H. Wang, and A. Han, "Effects of Fluid Medium Flow and Spatial Temperature Varation on Acoustophoretic Motion of Microparticles in Microfluidic Channels," Journal of the Acoustic Society of America (JASA), Vol. 139 (1), pp. 332-349 (2016)). Congratulations Han!

 

Nov. 2, 2015
John Buonocore joins as a new MS student in our lab. Welcome John.

 

Oct. 29, 2015
Shenyang Yang joins as a new MS student in our lab. Welcome Shenyang.

 

Sep. 1, 2015
Jose Wippold joins as a new PhD student in our lab. Welcome Jose.

 

Aug 20, 2015
We are leading a new National Science Foundation (NSF) project to develop a tool for studying biophysical and chemical properties of large populations of cells with single-cell resolution. This $1M project is supported through NSF's Major Research Instrument (MRI) program (see TAMU Engineering News story here).

 

Aug 18, 2015
Han Wang received the Oustanding Graduate Student Award (honorable distinction) from the Department of Electrical and Computer Engineering for his Ph.D. thesis work. Many congratulations Han!!

May 28, 2015
Han Wang receives his PhD. Thanks for all your hard work and many congratulations!!!

May 28, 2015
Keith Krenek receives the prestigious National Science Foundation (NSF) Graduate Research Fellowship (GRF). Many congratulations Keith, this is a great accomplishment (see news here).

May 8, 2015
Senior design project team Dale Julson, Jacob Hannusch, and Cameron Shaw, received the ConocoPhillips Award for Outstanding Capstone Project for their work on acoustofluidic devie based oil spill detection. Many congratulations, this is a great achievement.

May 7, 2015
Dr. Han receives the E. D. Brockett Professorship award for Engineering Contribution (see news for 2015 Faculty and Staff Award).

 

May 1, 2015
New building dedicated as the Frederick E. Giesecke Engineering Research Building. Click here to know more about this new building where our lab is now in.

April 24, 2015
The 2nd Texas A&M ENG-LIFE Workshop was successfully held on the Health Science Center campus with more than 140 participants, 13 oral presentations, and 58 posters. Many thanks to all the people who helped organize this event. Please click here for more on the workshop.

February 9, 2015
We just moved to a new building!

February 5, 2015
Dr. Jing Dai joins as a postdoctoral researcher. Welcome to our lab!

 

January 6, 2015
Visiting our new building (Engineering Research Building) where our lab will be moving into soon. Click here or the image for a panoramic view of the building!!!

December 18, 2014
Congratulations for your graduation, Dr. Hyunsoo Kim.

December 10, 2014
Celal Erbay's paper titled "High Performance Monolithic Power Management System with Dynamic Maximum Power Point Tracking for Microbial Fuel Cells" has been published in the journal Environmental Science & Technology (C. Erbay, S. Carreon-Bautista, E. Sanchez-Sinencio, and A. Han, “High Performance Monolithic Power Management System with Dynamic Maximum Power Point Tracking for Microbial Fuel Cells,” Environmental Science & Technology, Vol. 48, pp. 13992-13999, 2014). Congratulations Celal!

 

December 3, 2014
Jaewon receives the best poster award at the 2014 Society for Neuroscience (SfN)-TAMU Chapter Poster competition. Congratulations Jaewon.

 

November 6, 2014
Han Wang's paper titled "Microfluidic Geometric Metering-based Multi-Reagent Mixture Generator for Robust Live Cell Screening Array" has been published in the journal Biomedical Microdevices (H. Wang, J. Kim, A. Jayaraman, and A. Han, “Microfluidic Geometric Metering-based Multi-Reagent Mixture Generator for Robust Environmental Toxin Screening,” Biomedical Microdevices, Vol. 16 (6), pp. 887-896, 2014). Congratulations Han!

 

November 5, 2014
Prof. Han gives an interview on how microphysiological systems can be used to develop next-generation biologics to address one of the One Health Grand Challenge theme of "Accessible and Affordable Quality Healthcare". The interview is featured on the TAMU One Health Grand Challenge Website.

(Click here to see the news article)   (Click here to see the interview)

 

November 1, 2014
Our group presented 2 oral presentations and 5 posters at the MicroTAS 2014 held in San Antonio this year. Good performance everybody.

October 29, 2014
Prof. Han leads a rsearch initiative selected for theOne Health Grand Challenge theme "Accessible and Affordable Quality Healthcare". The title is "Miniature Tissues and Organs for Detection and Prevention of Diseases", focusing on developing next-generaiton biologics. (Click here to see the announcement)

 

October 28, 2014
Prof. Han receives a seed grant to lead a multidisciplinary team to better understand microbial communities through microfluidic lab-on-a-chip systems. The team hope to understand the principles underlying microbial communities through the development and use of microsystems technologies (e.g., microbial-communities-on-a- chip, lab-on-a-chip) that enable high-throughput, accurate, flexible, and low cost analysis and control of microbial communities in the laboratory.  (Click here to see the Texas A&M Engineering Experiment Station Announcement)

 

May 29, 2014
Prof. Han received the inaugural Engineering Genesis Award for Multidisciplinary Research during the TEES Inaugural Advisory Board meetin.Click below to see the TAMU Engineering News article.
(Click here to see the College of Engineering NEWS)

 

May 18, 2014
Our work on microfluidic systems for algal biofuel, including our recent cover article in the journal Lab on a Chip, has been featured in TAMU Engineering News. Click here for more details.

This work was also introduced on the BioNews Texas, a digital media platform focused on the biotechnology, life science and academic research industries in the state of Texas. Click here for the news "Texas A&M team develops lab-on-a-chip system for algal biofuel's growth".

 

May 8, 2014
Congratulations to Jonathan, Nathan, Taylor, and Deepak, our capstone project team "Biological Analysis with MicroFluidics" in receiving the first place in the Department of Electrical and Computer Engineering at the 2014 TAMU Engineering Project Showcase. More than 600 undergraduates participated in this event. Very well done!!

 

April 11, 2014
Dr. Jaewon Park's poster took first place at the 6th Annual Texas A&M Institute for Neuroscience (TAMIN) Symposium. The title of his poster is "A Microchip for Axon Growth Analysis". His work is co-advised with Prof. Jianrong Li from the College of Veterinary Medicine. Congratulations Jaewon!

 

March 20, 2014
Prof. Han receives the Eugene Webb Faculty Fellow Award from the College of Engineering. See below for full news.
(Click here to see the College of Engineering NEWS)

 

February 10, 2014
Han Wangs' paper titled "Microfluidic Acoustophoretic Force Based Low Concentration Oil Separation and Detection from Environment" has been published in the journal Lab on a Chip (H.Wang, Z.Liu, C. Koo, S. Kim, Y. Cho, D. -Y. Jang, Y. -J. Kim, and A. Han, “Microfluidic Acoustophoretic Force Based Low Concentration Oil Separation and Detection from Environment” Lab on a Chip,Vol. 14, pp. 947-956 (2014)). Congratulations Han!

 

February 4, 2014
Changwoo Ban's paper titled "Liquid- Phase Capillary Etching of Poly(Dimethylsiloxane) Microchannels With Tetra-n-Butylammonium Fluoride" has been published in the journal J. Microelectromechanical Systems (C. Ban, J. Park, D. -Y. Jang,and A. Han, “Liquid- Phase Capillary Etching of Poly(Dimethylsiloxane) Microchannels With Tetra-n-Butylammonium Flouride,” J. Microelectricalmechanical Systems (JMEMS), Vol.23 (2), pp. 276-283 (2014). Congratulations!

 

January 23, 2014
Hyun Soo Kim's paper titled "A Microfluidic Photobioreactor Array Demonstrating High-Throughput Screening for Microalgal Oil Production" has been published in the journal Lab on a Chip (H. S. Kim, T. L. Weiss, H. R. Thapa, T. P. Devarenne, andA. Han, “A Microfluidic Photobioreactor Array Demonstrating High -Throughput Screening for Microalgal Oil Production,” Lab on a Chip, Vol. 14 (8), pp. 1379-1482 (2014) Published as Fron Cover Selected as a Lab on a Chip HOT Article.). Congratulations Hyun Soo!

 

January 13, 2014
Chiwan Koo's paper titled "Microfluidically Cryo-Cooled Spiral Microcoils with Inductive Coupling for MR Microscopy" has been published in the IEEE Transactions on Biomedical Engineering (C. Koo, R. F. Godley, M. P. McDougall, S. M. Wright, and A. Han, “Microfluidically Cryo-Cooled Spiral Microcoils with Inductive Coupling for MR Microscopy,” IEEE Transactions on Biomedical Engineering, Vol. 61 (1), pp. 76-84, 2014). Congratulations Chiwan!

 

January 10, 2014
Jaewon Park's paper titled "A Microchip for Quantitative Analysis of CNS Axon Growth under Localized Biomolecular Treatment" has been published in the Journal of Neuroscience Method (J. Park, S. Kim, S. I. Park, Y. Choe, J. Li, and A. Han, “A Microchip for Quantitative Analysis of CNS Axon Growth under Localized Biomolecular Treatments,” Journal of Neuroscience Methods, Vol. 21, pp. 166-174, 2014). Congratulations Jaewon!

 

December 17, 2013
Chiwan Koo's paper titled "Development of a Lab-on-a-Chip Real-Time PCR System for Portable Plant Disease Diagnostics" has been published in the journal PLoS ONE (C. Koo, M. Malapi-Wight, H. Kim, O. S. Cifci, V. Vaughn, B. Ma, S. Kim, H. Abdel-Raziq, K. Ong, Y. –K. Jo, D. Gross, W. –B. Shim, and A. Han, PLoS ONE, Vol. 8 (12), e82704 (2013)). Congratulations Chiwan!

 

November 30, 2013
The first Texas A&M Eng-LIFE Workshop "At the Interface of Engineering and Life Sciences" that we hosted, together with the department of Electrical and Computer Engineering, the Dwight Look College of Engineering, the Texas A&M Health Science Center, and the College of Veterinary Medicine was a great success with more than 120 attendees. Please click here to see the website for the program as well as a TAMU College of Engineering news article for more details.

 

October 24, 2013
Chiwan Koo's co-authored paper titled "A Frequency Reconfigurable Patch Antenna Using Liquid Metal as a Switching Mechanism" has been published in the journal Electronic Letters (M. Kelley, C. Koo, H. McQuilken, B. Lawrence, S. Li, A. Han, and G. Huff, Electronic Letters, Vol. 49, pp. 1370-1371 (2013). Congratulations Chiwan!

 

August 26, 2013
Se Hoon Jeong, Sergio Waqued, and Yusuf Dorgan joined as graduate students to our lab. Welcome!

 

August 16, 2013
Chiwan Koo received his Ph.D for his work titled "Microfluidically Cryo-Cooled Planar Coils for Magnetic Resonance Imaging". Thanks for all your hard work!

 

August 7, 2013
Jaewon Park's paper titled "Microchemostat Array with Small-Volume Fraction Replenishment for Steady-State Microbial Culture" has been published in the journal Lab Chip (J. Park, J. Wu, M. Polymenis, and A. Han, Lab Chip, Vol. 13, pp. 4217-4224 (2013)). Congratulations Jaewon!

 

April 29, 2013
Chiwan Koo's co-authored paper titled "Ratiometric Temperature Imaging Using Environment-Insensitive Luminescence of Mn-doped core–shell nanocrystals" has been published in the journal Lab Chip (Y. Park, C. Koo, H. -Y. Chen, A. Han, and D. H. Son, Lab Chip, Vol. 5, pp. 4944-4950 (2013)). Congratulations Chiwan!

 

April 24, 2013
Whitney Longsine-Parker and Han's co-first author paper titled "Microfluidic Electro-Sonoporation: A Multi-Modal Cell Poration Methodology through Simultaneous Application of Electric Field and Ultrasonic Wave" has been published in the journal Lab Chip (*W. Longsine-Parker, *H. Wang, C. Koo, J. Kim, B. J. Kim, A. Jayaraman, and A. Han, Lab Chip, Vol. 13, pp. 2144-2152 (2013) (*These authors contributed equally as co-first authors)) . Congratulations Whitney and Han!

 

May 3, 2013
Our AggieE-Challenge team (Taufik Ridha, Melinda McClure, John Piatt, Tiffany Hargett, Santiago Aguiar, Diana Lainez, and Jiyeong Kwon) received the third-place award at the Texas A&M Engineering Showcase. Congratulations!!! Click here to see the TAMU Engineering News article.

April 25, 2013
Prof. Arum Han becomes TEES Fellow. Click here to see the TAMU Engineering News article.

 

April 5, 2013
We have published a review paper titled "Microfabricated Devices in Microbial Bioenergy Sciences" in the Journal Trends in Biotechnology. Click here to see the TAMU Engineering News article.

 

January 10, 2013
Nebras Sobahi joins ours lab as a new M.S. student. Welcome Nebras.